Loricrin and NRF2 Coordinate Cornification

Cornification involves cytoskeletal cross-linkages in corneocytes (the brick) and the secretion of lipids/adhesion structures to the interstitial space (the mortar). Because the assembly of lipid envelopes precedes corneocyte maturation, loricrin is supposed to be dispensable for the protection agai...

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Main Authors: Yosuke Ishitsuka, Tatsuya Ogawa, Yoshiyuki Nakamura, Noriko Kubota, Yasuhiro Fujisawa, Rei Watanabe, Naoko Okiyama, Manabu Fujimoto, Dennis R. Roop, Akemi Ishida-Yamamoto
Format: article
Language:EN
Published: Elsevier 2022
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Online Access:https://doaj.org/article/3f586b8bb46046aeb57214cd1957d59e
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