Reducing uncertainty in within-host parameter estimates of influenza infection by measuring both infectious and total viral load.

For in vivo studies of influenza dynamics where within-host measurements are fit with a mathematical model, infectivity assays (e.g. 50% tissue culture infectious dose; TCID50) are often used to estimate the infectious virion concentration over time. Less frequently, measurements of the total (infec...

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Autores principales: Stephen M Petrie, Teagan Guarnaccia, Karen L Laurie, Aeron C Hurt, Jodie McVernon, James M McCaw
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/3f887a85c800406bacc3e6f5cdb407ea
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