Reducing uncertainty in within-host parameter estimates of influenza infection by measuring both infectious and total viral load.
For in vivo studies of influenza dynamics where within-host measurements are fit with a mathematical model, infectivity assays (e.g. 50% tissue culture infectious dose; TCID50) are often used to estimate the infectious virion concentration over time. Less frequently, measurements of the total (infec...
Guardado en:
Autores principales: | Stephen M Petrie, Teagan Guarnaccia, Karen L Laurie, Aeron C Hurt, Jodie McVernon, James M McCaw |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/3f887a85c800406bacc3e6f5cdb407ea |
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