Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling.

<h4>Background</h4>Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles. However, in certain clinical situations including oral lichen planus, K15 is induced i...

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Auteurs principaux: Amrita Bose, Muy-Teck Teh, Iain L Hutchison, Hong Wan, Irene M Leigh, Ahmad Waseem
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/3f8ac37338fc45318d3ddac4d13c4789
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