Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling.

<h4>Background</h4>Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles. However, in certain clinical situations including oral lichen planus, K15 is induced i...

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Autores principales: Amrita Bose, Muy-Teck Teh, Iain L Hutchison, Hong Wan, Irene M Leigh, Ahmad Waseem
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/3f8ac37338fc45318d3ddac4d13c4789
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