MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function
Acute liver injury (ALI) raises high mortality rates due to a rapid pathological process. MCC950, a highly selective nod-like receptor family pyrin domain containing 3 (NLRP3) inhibitor, has already been reported to show strong hepatoprotective effects in many different liver diseases. In this study...
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Auteurs principaux: | Wei Yan, Yingchun Shen, Jinny Huang, Ling Lu, Qian Zhang |
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Format: | article |
Langue: | EN |
Publié: |
Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/3fd6ab646b794c8082d4b3fd2ab6caef |
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