Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy

Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy

Abstract MicroRNA-125b, the first microRNA to be identified, is known to promote cardiomyocyte maturation from embryonic stem cells; however, its physiological role remains unclear. To investigate the role of miR-125b in cardiovascular biology, cardiac-specific miR-125b-1 knockout mice were generate...

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Main Authors: Chen-Yun Chen, Desy S. Lee, Oi Kuan Choong, Sheng-Kai Chang, Tien Hsu, Martin W. Nicholson, Li-Wei Liu, Po-Ju Lin, Shu-Chian Ruan, Shu-Wha Lin, Chung-Yi Hu, Patrick C. H. Hsieh
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/4026093012a24238a07b583c66e4a5a9
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https://doaj.org/article/4026093012a24238a07b583c66e4a5a9

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