Angiotensin-(1–7) treatment blocks lipopolysaccharide-induced organ damage, platelet dysfunction, and IL-6 and nitric oxide production in rats

Abstract Sepsis can lead to shock, multiple organ failure, and even death. Platelets play an active role in the pathogenesis of sepsis-induced multiple organ failure. Angiotensin (Ang)-(1–7), a biologically active peptide, counteracts various effects of Ang II and attenuates inflammatory responses,...

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Bibliographic Details
Main Authors: Hsin-Jung Tsai, Chih-Chin Shih, Kuang-Yi Chang, Mei-Hui Liao, Wen-Jinn Liaw, Chin-Chen Wu, Cheng-Ming Tsao
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/402d0fcc278347fba3c87beaac688ad5
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