Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F

The vitamin B12 importer BtuCD-F is a type II ATP-binding cassette transporter. Here the authors use single-molecule fluorescence techniques to analyse ATP hydrolysis and substrate transport in individual BtuCD-F complexes embedded in liposomes, and propose a transport model.

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Autores principales:	Joris M. H. Goudsmits, Dirk Jan Slotboom, Antoine M. van Oijen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/403f34f7a6fc4b4897cd19e63f9c11cd
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spelling	oai:doaj.org-article:403f34f7a6fc4b4897cd19e63f9c11cd2021-12-02T14:40:48ZSingle-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F10.1038/s41467-017-01815-72041-1723https://doaj.org/article/403f34f7a6fc4b4897cd19e63f9c11cd2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01815-7https://doaj.org/toc/2041-1723The vitamin B12 importer BtuCD-F is a type II ATP-binding cassette transporter. Here the authors use single-molecule fluorescence techniques to analyse ATP hydrolysis and substrate transport in individual BtuCD-F complexes embedded in liposomes, and propose a transport model.Joris M. H. GoudsmitsDirk Jan SlotboomAntoine M. van OijenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joris M. H. Goudsmits Dirk Jan Slotboom Antoine M. van Oijen Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
description	The vitamin B12 importer BtuCD-F is a type II ATP-binding cassette transporter. Here the authors use single-molecule fluorescence techniques to analyse ATP hydrolysis and substrate transport in individual BtuCD-F complexes embedded in liposomes, and propose a transport model.
format	article
author	Joris M. H. Goudsmits Dirk Jan Slotboom Antoine M. van Oijen
author_facet	Joris M. H. Goudsmits Dirk Jan Slotboom Antoine M. van Oijen
author_sort	Joris M. H. Goudsmits
title	Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
title_short	Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
title_full	Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
title_fullStr	Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
title_full_unstemmed	Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F
title_sort	single-molecule visualization of conformational changes and substrate transport in the vitamin b12 abc importer btucd-f
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/403f34f7a6fc4b4897cd19e63f9c11cd
work_keys_str_mv	AT jorismhgoudsmits singlemoleculevisualizationofconformationalchangesandsubstratetransportinthevitaminb12abcimporterbtucdf AT dirkjanslotboom singlemoleculevisualizationofconformationalchangesandsubstratetransportinthevitaminb12abcimporterbtucdf AT antoinemvanoijen singlemoleculevisualizationofconformationalchangesandsubstratetransportinthevitaminb12abcimporterbtucdf
_version_	1718390105618513920

Single-molecule visualization of conformational changes and substrate transport in the vitamin B12 ABC importer BtuCD-F

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