Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

ABSTRACT When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-, leucine-rich-repeat-containing proteins (NLR proteins) that bind and activate caspase-1. We report that these inflammasome components also regulate...

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Autores principales: Brenda G. Byrne, Jean-Francois Dubuisson, Amrita D. Joshi, Jenny J. Persson, Michele S. Swanson
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://doaj.org/article/404522b7c4ea440996363903bb320f02
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