Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection
ABSTRACT When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-, leucine-rich-repeat-containing proteins (NLR proteins) that bind and activate caspase-1. We report that these inflammasome components also regulate...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/404522b7c4ea440996363903bb320f02 |
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