Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies.

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies.

The emergence of high-throughput, next-generation sequencing technologies has dramatically altered the way we assess genomes in population genetics and in cancer genomics. Currently, there are four commonly used whole-genome sequencing platforms on the market: Illumina's HiSeq2000, Life Technol...

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Autores principales: Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul Northcott, Barbara Hutter, Natalie Jäger, Marcel Kool, Michael Taylor, Peter Lichter, Stefan Pfister, Stephan Wolf, Benedikt Brors, Roland Eils
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/408b0b951a5e4349acf88afcb63b782b
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