Natural variant frequencies across domains from different sarcomere proteins cross-correlate to identify inter-protein contacts associated with cardiac muscle function and disease
Abstract Coordinated sarcomere proteins produce contraction force for muscle shortening. In human ventriculum they include the cardiac myosin motor (βmys), repetitively converting ATP free energy into work, and myosin binding protein C (MYBPC3) that in complex with βmys is regulatory. Single nucleot...
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| Formato: | article |
| Lenguaje: | EN |
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Springer
2021
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| Acceso en línea: | https://doaj.org/article/40cc9693b4064125aff67ab9a117cf45 |
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