Simian Immunodeficiency Virus-Infected Memory CD4<sup>+</sup> T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS

Simian Immunodeficiency Virus-Infected Memory CD4<sup>+</sup> T Cells Infiltrate to the Site of Infected Macrophages in the Neuroparenchyma of a Chronic Macaque Model of Neurological Complications of AIDS

ABSTRACT Simian immunodeficiency virus (SIV)-infected nonhuman primates can serve as a relevant model for AIDS neuropathogenesis. Current SIV-induced encephalitis (SIVE)/neurological complications of AIDS (neuroAIDS) models are generally associated with rapid progression to neuroAIDS, which does not...

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Bibliographic Details
Main Authors: Cheri A. Lee, Erin Beasley, Karthikeyan Sundar, Margery Smelkinson, Carol Vinton, Claire Deleage, Kenta Matsuda, Fan Wu, Jake D. Estes, Bernard A. P. Lafont, Jason M. Brenchley, Vanessa M. Hirsch
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
AIDS
CD4 T cells
central nervous system infections
encephalitis
inflammation
macrophages
Microbiology
QR1-502
Online Access:https://doaj.org/article/40f2856af6be4f2a8fb0aa9a0ec10809
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