Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Abstract Uncharacterized and unannotated open-reading frames, which we refer to as novel open reading frames (nORFs), may sometimes encode peptides that remain unexplored for novel therapeutic opportunities. To our knowledge, no systematic identification and characterization of transcripts encoding...

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Autores principales: Chaitanya Erady, Adam Boxall, Shraddha Puntambekar, N. Suhas Jagannathan, Ruchi Chauhan, David Chong, Narendra Meena, Apurv Kulkarni, Bhagyashri Kasabe, Kethaki Prathivadi Bhayankaram, Yagnesh Umrania, Adam Andreani, Jean Nel, Matthew T. Wayland, Cristina Pina, Kathryn S. Lilley, Sudhakaran Prabakaran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Genetics
QH426-470
Acceso en línea:https://doaj.org/article/410f193223914d33badf65ab4ce92412
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https://doaj.org/article/410f193223914d33badf65ab4ce92412

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