Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade.
Toxoplasma gondii is an orally acquired pathogen that induces strong IFN-γ based immunity conferring protection but that can also be the cause of immunopathology. The response in mice is driven in part by well-characterized MyD88-dependent signaling pathways. Here we focus on induction of less well...
Saved in:
Main Authors: | Lindsay M Snyder, Claire M Doherty, Heather L Mercer, Eric Y Denkers |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/414ff491d4484a61aadcd0d8355b9edc |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.
by: Igor L Calil, et al.
Published: (2014) -
Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei.
by: Shuang Zhang, et al.
Published: (2012) -
Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
by: Jiro Sakai, et al.
Published: (2017) -
Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
by: Chengcheng Li, et al.
Published: (2017) -
HPV-transformed cells exhibit altered HMGB1-TLR4/MyD88-SARM1 signaling axis
by: Mirian Galliote Morale, et al.
Published: (2018)