Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol

The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and...

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Autores principales: L. A. Yakovishin, V. I. Grishkovets, E. N. Korzh, I. V. Golovchenko, A. A. Nagirnyak
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RU
Publicado: Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina 2020
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spelling oai:doaj.org-article:4187339dd82f41749a929f5e42f016512021-12-01T05:53:10ZMolecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol2411-141410.15826/chimtech.2020.7.4.02https://doaj.org/article/4187339dd82f41749a929f5e42f016512020-12-01T00:00:00Zhttps://journals.urfu.ru/index.php/chimtech/article/view/4800https://doaj.org/toc/2411-1414The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex.L. A. YakovishinV. I. GrishkovetsE. N. KorzhI. V. GolovchenkoA. A. NagirnyakUralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina articletriterpene glycosideshederasaponin ccholesterolmolecular complexChemistryQD1-999ENRUChimica Techno Acta, Vol 7, Iss 4, Pp 150-153 (2020)
institution DOAJ
collection DOAJ
language EN
RU
topic triterpene glycosides
hederasaponin c
cholesterol
molecular complex
Chemistry
QD1-999
spellingShingle triterpene glycosides
hederasaponin c
cholesterol
molecular complex
Chemistry
QD1-999
L. A. Yakovishin
V. I. Grishkovets
E. N. Korzh
I. V. Golovchenko
A. A. Nagirnyak
Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
description The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex.
format article
author L. A. Yakovishin
V. I. Grishkovets
E. N. Korzh
I. V. Golovchenko
A. A. Nagirnyak
author_facet L. A. Yakovishin
V. I. Grishkovets
E. N. Korzh
I. V. Golovchenko
A. A. Nagirnyak
author_sort L. A. Yakovishin
title Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
title_short Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
title_full Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
title_fullStr Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
title_full_unstemmed Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol
title_sort molecular complexation of hederasaponin c with cholesterol in aqueous isopropyl alcohol
publisher Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina
publishDate 2020
url https://doaj.org/article/4187339dd82f41749a929f5e42f01651
work_keys_str_mv AT layakovishin molecularcomplexationofhederasaponincwithcholesterolinaqueousisopropylalcohol
AT vigrishkovets molecularcomplexationofhederasaponincwithcholesterolinaqueousisopropylalcohol
AT enkorzh molecularcomplexationofhederasaponincwithcholesterolinaqueousisopropylalcohol
AT ivgolovchenko molecularcomplexationofhederasaponincwithcholesterolinaqueousisopropylalcohol
AT aanagirnyak molecularcomplexationofhederasaponincwithcholesterolinaqueousisopropylalcohol
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