A prion accelerates proliferation at the expense of lifespan

In fluctuating environments, switching between different growth strategies, such as those affecting cell size and proliferation, can be advantageous to an organism. Trade-offs arise, however. Mechanisms that aberrantly increase cell size or proliferation—such as mutations or chemicals that interfere...

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Autores principales: David M Garcia, Edgar A Campbell, Christopher M Jakobson, Mitsuhiro Tsuchiya, Ethan A Shaw, Acadia L DiNardo, Matt Kaeberlein, Daniel F Jarosz
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
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Acceso en línea:https://doaj.org/article/418f66c5630d4db19a8f8ec90c1a9440
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