Intrahost Dynamics of Antiviral Resistance in Influenza A Virus Reflect Complex Patterns of Segment Linkage, Reassortment, and Natural Selection
ABSTRACT Resistance following antiviral therapy is commonly observed in human influenza viruses. Although this evolutionary process is initiated within individual hosts, little is known about the pattern, dynamics, and drivers of antiviral resistance at this scale, including the role played by reass...
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Auteurs principaux: | Matthew B. Rogers, Timothy Song, Robert Sebra, Benjamin D. Greenbaum, Marie-Eve Hamelin, Adam Fitch, Alan Twaddle, Lijia Cui, Edward C. Holmes, Guy Boivin, Elodie Ghedin |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2015
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Sujets: | |
Accès en ligne: | https://doaj.org/article/41a17f66d22443bfbe1717f3d29a087a |
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