NHC-catalyzed atropoenantioselective synthesis of axially chiral biaryl amino alcohols via a cooperative strategy
Axially chiral biaryl amino-alcohols play a pivotal role in organic synthesis and drug discovery. Here, the authors report a cooperative strategy consisting of desymmetrization followed by kinetic resolution to deliver non-classical NOBIN derivatives in high yields and enantioselectivity via NHC cat...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
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| Accès en ligne: | https://doaj.org/article/420335355ac145a7a85467d92e8d419b |
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