Anti-metastatic effect of GV1001 on prostate cancer cells; roles of GnRHR-mediated Gαs-cAMP pathway and AR-YAP1 axis

Abstract Background Gonadotropin-releasing hormone receptor (GnRHR) transmits its signal via two major Gα-proteins, primarily Gαq and Gαi. However, the precise mechanism underlying the functions of Gαs signal in prostate cancer cells is still unclear. We have previously identified that GV1001, a fra...

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Bibliographic Details
Main Authors: Ji Won Kim, Miso Park, Suntae Kim, Sung Chul Lim, Hyung Shik Kim, Keon Wook Kang
Format: article
Language:EN
Published: BMC 2021
Subjects:
AR
Online Access:https://doaj.org/article/4211061cf8bf472e97ea786f0322647f
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