Effect of Piperine Pretreatment on Biochemical Profiles of Acetaminophen-Induced Hepatotoxicity in Rats

BACKGROUND AND OBJECTIVE: Acetaminophen overdose is the most frequent cause of liver injuries. N-acetyl-p-benzoquinone imine (NAPQI) has been proposed as the toxic metabolite of acetaminophen induced by cytochrome P-450. Piperine has antioxidant activities and has been introduced as an inhibitor of...

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Autores principales: MT Kazemi, M Pour Nasrollah, MM Rezaei, GH.A Jorsaraei, GH Maliji, S Kazemi, E Zabihi, M Pouramir, AA Moghadamnia
Formato: article
Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2012
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Acceso en línea:https://doaj.org/article/424fecfe063148669e9378e9f9cbf2b6
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