Effect of Piperine Pretreatment on Biochemical Profiles of Acetaminophen-Induced Hepatotoxicity in Rats
BACKGROUND AND OBJECTIVE: Acetaminophen overdose is the most frequent cause of liver injuries. N-acetyl-p-benzoquinone imine (NAPQI) has been proposed as the toxic metabolite of acetaminophen induced by cytochrome P-450. Piperine has antioxidant activities and has been introduced as an inhibitor of...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN FA |
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Babol University of Medical Sciences
2012
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| Accès en ligne: | https://doaj.org/article/424fecfe063148669e9378e9f9cbf2b6 |
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