Effect of Piperine Pretreatment on Biochemical Profiles of Acetaminophen-Induced Hepatotoxicity in Rats
BACKGROUND AND OBJECTIVE: Acetaminophen overdose is the most frequent cause of liver injuries. N-acetyl-p-benzoquinone imine (NAPQI) has been proposed as the toxic metabolite of acetaminophen induced by cytochrome P-450. Piperine has antioxidant activities and has been introduced as an inhibitor of...
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Autores principales: | MT Kazemi, M Pour Nasrollah, MM Rezaei, GH.A Jorsaraei, GH Maliji, S Kazemi, E Zabihi, M Pouramir, AA Moghadamnia |
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Formato: | article |
Lenguaje: | EN FA |
Publicado: |
Babol University of Medical Sciences
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/424fecfe063148669e9378e9f9cbf2b6 |
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