β1 integrin signaling maintains human epithelial progenitor cell survival in situ and controls proliferation, apoptosis and migration of their progeny.

β1 integrin regulates multiple epithelial cell functions by connecting cells with the extracellular matrix (ECM). While β1 integrin-mediated signaling in murine epithelial stem cells is well-studied, its role in human adult epithelial progenitor cells (ePCs) in situ remains to be defined. Using micr...

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Bibliographic Details
Main Authors: Nancy Ernst, Arzu Yay, Tamás Bíró, Stephan Tiede, Martin Humphries, Ralf Paus, Jennifer E Kloepper
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
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Online Access:https://doaj.org/article/42510628733a437d971971fe3a74d93b
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