HeurAA: accurate and fast detection of genetic variations with a novel heuristic amplicon aligner program for next generation sequencing.
Next generation sequencing (NGS) of PCR amplicons is a standard approach to detect genetic variations in personalized medicine such as cancer diagnostics. Computer programs used in the NGS community often miss insertions and deletions (indels) that constitute a large part of known human mutations. W...
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Autores principales: | , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Acceso en línea: | https://doaj.org/article/4254b9985fbd4005a6b0db7fce1d59ee |
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