The anti-diabetic drug metformin reduces BACE1 protein level by interfering with the MID1 complex.
Alzheimer's disease (AD), the most common form of dementia in the elderly, is characterized by two neuropathological hallmarks: senile plaques, which are composed of Aβ peptides, and neurofibrillary tangles, which are composed of hyperphosphorylated TAU protein. Diabetic patients with dysregula...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2014
|
| Subjects: | |
| Online Access: | https://doaj.org/article/42649d0e94c24c4ca876da763496d3f4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|