Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits <italic toggle="yes">Ex Vivo</italic> Lipopolysaccharide-Induced Inflammatory Responses
ABSTRACT Histone deacetylase inhibitors (HDACi) modulate the transcriptional activity of all cells, including innate and adaptive immune cells. Therefore, we aimed to evaluate immunological effects of treatment with the HDACi panobinostat in HIV-infected patients during a clinical phase IIa latency...
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| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2018
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/42a41f93e9564a62ab717ed0df2a75eb |
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