Medial prefrontal area reductions, altered expressions of cholecystokinin, parvalbumin, and activating transcription factor 4 in the corticolimbic system, and altered emotional behavior in a progressive rat model of type 2 diabetes.

Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and regional area reductions and increased cholecysto...

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Autores principales: Ryosuke Ochi, Naoto Fujita, Natsuki Goto, Kaho Takaishi, Takaya Oshima, Son Tien Nguyen, Hisao Nishijo, Susumu Urakawa
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/42ce49a68d344f01aa3723b52e1bf345
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