H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines

High-grade gliomas represent the most lethal class of pediatric tumors, and their resistance to both radio- and chemotherapy is associated with a poor prognosis. Recurrent mutations affecting histone genes drive the tumorigenesis of some pediatric high-grade gliomas, and H3K27M mutations are notably...

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Autores principales:	Andria Rakotomalala, Quentin Bailleul, Clara Savary, Mélanie Arcicasa, Maud Hamadou, Paul Huchedé, Audrey Hochart, Audrey Restouin, Remy Castellano, Yves Collette, Emma Dieny, Audrey Vincent, Pierre-Olivier Angrand, Xuefen Le Bourhis, Pierre Leblond, Alessandro Furlan, Marie Castets, Eddy Pasquier, Samuel Meignan
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	H3.3K27M glioma child resistance to therapies radiotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/42cf81e91f7b4d65b7024047c01962a6
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H3.3K27M Mutation Controls Cell Growth and Resistance to Therapies in Pediatric Glioma Cell Lines

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