CCDC102B confers risk of low vision and blindness in high myopia

CCDC102B confers risk of low vision and blindness in high myopia

Myopic maculopathy is a complication of myopia that often progresses to blindness. Here, in a genome-wide association study, Hosoda et al. find that rs11873439 intronic to CCDC102B is associated with myopic maculopathy, but not with myopia, thus representing a risk factor independent of myopia.

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Bibliographic Details
Main Authors: Yoshikatsu Hosoda, Munemitsu Yoshikawa, Masahiro Miyake, Yasuharu Tabara, Noriaki Shimada, Wanting Zhao, Akio Oishi, Hideo Nakanishi, Masayuki Hata, Tadamichi Akagi, Sotaro Ooto, Natsuko Nagaoka, Yuxin Fang, Nagahama Study group, Kyoko Ohno-Matsui, Ching-Yu Cheng, Seang Mei Saw, Ryo Yamada, Fumihiko Matsuda, Akitaka Tsujikawa, Kenji Yamashiro
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/4307c365be5b4c14888073af32c95a99
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https://doaj.org/article/4307c365be5b4c14888073af32c95a99

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