CCDC102B confers risk of low vision and blindness in high myopia
Myopic maculopathy is a complication of myopia that often progresses to blindness. Here, in a genome-wide association study, Hosoda et al. find that rs11873439 intronic to CCDC102B is associated with myopic maculopathy, but not with myopia, thus representing a risk factor independent of myopia.
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Nature Portfolio
2018
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oai:doaj.org-article:4307c365be5b4c14888073af32c95a992021-12-02T16:49:16ZCCDC102B confers risk of low vision and blindness in high myopia10.1038/s41467-018-03649-32041-1723https://doaj.org/article/4307c365be5b4c14888073af32c95a992018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03649-3https://doaj.org/toc/2041-1723Myopic maculopathy is a complication of myopia that often progresses to blindness. Here, in a genome-wide association study, Hosoda et al. find that rs11873439 intronic to CCDC102B is associated with myopic maculopathy, but not with myopia, thus representing a risk factor independent of myopia.Yoshikatsu HosodaMunemitsu YoshikawaMasahiro MiyakeYasuharu TabaraNoriaki ShimadaWanting ZhaoAkio OishiHideo NakanishiMasayuki HataTadamichi AkagiSotaro OotoNatsuko NagaokaYuxin FangNagahama Study groupKyoko Ohno-MatsuiChing-Yu ChengSeang Mei SawRyo YamadaFumihiko MatsudaAkitaka TsujikawaKenji YamashiroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-7 (2018) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Yoshikatsu Hosoda Munemitsu Yoshikawa Masahiro Miyake Yasuharu Tabara Noriaki Shimada Wanting Zhao Akio Oishi Hideo Nakanishi Masayuki Hata Tadamichi Akagi Sotaro Ooto Natsuko Nagaoka Yuxin Fang Nagahama Study group Kyoko Ohno-Matsui Ching-Yu Cheng Seang Mei Saw Ryo Yamada Fumihiko Matsuda Akitaka Tsujikawa Kenji Yamashiro CCDC102B confers risk of low vision and blindness in high myopia |
| description |
Myopic maculopathy is a complication of myopia that often progresses to blindness. Here, in a genome-wide association study, Hosoda et al. find that rs11873439 intronic to CCDC102B is associated with myopic maculopathy, but not with myopia, thus representing a risk factor independent of myopia. |
| format |
article |
| author |
Yoshikatsu Hosoda Munemitsu Yoshikawa Masahiro Miyake Yasuharu Tabara Noriaki Shimada Wanting Zhao Akio Oishi Hideo Nakanishi Masayuki Hata Tadamichi Akagi Sotaro Ooto Natsuko Nagaoka Yuxin Fang Nagahama Study group Kyoko Ohno-Matsui Ching-Yu Cheng Seang Mei Saw Ryo Yamada Fumihiko Matsuda Akitaka Tsujikawa Kenji Yamashiro |
| author_facet |
Yoshikatsu Hosoda Munemitsu Yoshikawa Masahiro Miyake Yasuharu Tabara Noriaki Shimada Wanting Zhao Akio Oishi Hideo Nakanishi Masayuki Hata Tadamichi Akagi Sotaro Ooto Natsuko Nagaoka Yuxin Fang Nagahama Study group Kyoko Ohno-Matsui Ching-Yu Cheng Seang Mei Saw Ryo Yamada Fumihiko Matsuda Akitaka Tsujikawa Kenji Yamashiro |
| author_sort |
Yoshikatsu Hosoda |
| title |
CCDC102B confers risk of low vision and blindness in high myopia |
| title_short |
CCDC102B confers risk of low vision and blindness in high myopia |
| title_full |
CCDC102B confers risk of low vision and blindness in high myopia |
| title_fullStr |
CCDC102B confers risk of low vision and blindness in high myopia |
| title_full_unstemmed |
CCDC102B confers risk of low vision and blindness in high myopia |
| title_sort |
ccdc102b confers risk of low vision and blindness in high myopia |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/4307c365be5b4c14888073af32c95a99 |
| work_keys_str_mv |
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| _version_ |
1718383392453558272 |