Short-chain ketone production by engineered polyketide synthases in Streptomyces albus

Mutating natural enzymes is effective in broadening the substrate or product range, but generally leads to reduced titers. Here the authors engineer hybrid polyketide synthases for efficient production of short-chain ketones from plant biomass hydrolysates in Streptomyces, which can increase the oct...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Satoshi Yuzawa, Mona Mirsiaghi, Renee Jocic, Tatsuya Fujii, Fabrice Masson, Veronica T. Benites, Edward E. K. Baidoo, Eric Sundstrom, Deepti Tanjore, Todd R. Pray, Anthe George, Ryan W. Davis, John M. Gladden, Blake A. Simmons, Leonard Katz, Jay D. Keasling
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/43191a49361742d58a6a635e4ab9761b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!