Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4<sup>+</sup> T Cell Line

ABSTRACT Next-generation sequencing (NGS) enables the highly sensitive measurement of whole transcriptomes. We report the first application to our knowledge of this technology to the analysis of RNA from a CD4+ T cell line infected with intact HIV. We sequenced the total mRNA from infected cells and...

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Autores principales: Stewart T. Chang, Pavel Sova, Xinxia Peng, Jeffrey Weiss, G. Lynn Law, Robert E. Palermo, Michael G. Katze
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://doaj.org/article/4335629fcdcd4a7c9458980a08e6dea5
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