Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4<sup>+</sup> T Cell Line
ABSTRACT Next-generation sequencing (NGS) enables the highly sensitive measurement of whole transcriptomes. We report the first application to our knowledge of this technology to the analysis of RNA from a CD4+ T cell line infected with intact HIV. We sequenced the total mRNA from infected cells and...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2011
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Acceso en línea: | https://doaj.org/article/4335629fcdcd4a7c9458980a08e6dea5 |
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