Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4<sup>+</sup> T Cell Line
ABSTRACT Next-generation sequencing (NGS) enables the highly sensitive measurement of whole transcriptomes. We report the first application to our knowledge of this technology to the analysis of RNA from a CD4+ T cell line infected with intact HIV. We sequenced the total mRNA from infected cells and...
Guardado en:
Autores principales: | Stewart T. Chang, Pavel Sova, Xinxia Peng, Jeffrey Weiss, G. Lynn Law, Robert E. Palermo, Michael G. Katze |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4335629fcdcd4a7c9458980a08e6dea5 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Next-Generation Sequencing of Small RNAs from HIV-Infected Cells Identifies Phased microRNA Expression Patterns and Candidate Novel microRNAs Differentially Expressed upon Infection
por: Stewart T. Chang, et al.
Publicado: (2013) -
CD161<sup>+</sup> CD4<sup>+</sup> T Cells Harbor Clonally Expanded Replication-Competent HIV-1 in Antiretroviral Therapy-Suppressed Individuals
por: Xiaomin Li, et al.
Publicado: (2019) -
Phenotype remodeling in neutrophilic granulocyte subsets CD64<sup>-</sup>CD32<sup>+</sup>CD16<sup>+</sup>CD11B<sup>+</sup>NG, CD64<sup>+</sup>CD32<sup>+</sup>CD16<sup>+</sup>CD11B<sup>+</sup>NG in <i>de novo</i> experimental model of viral-bacterial infection <i>in vitro</i>
por: I. V. Nesterova, et al.
Publicado: (2021) -
EFFECTS OF γс-CYTOKINES (IL-2, IL-7 AND IL-15) UPON IN VITRO MATURATION AND DIFFERENTIATION OF CD4<sup>+</sup>CD45RО<sup>+</sup>/CD8<sup>+</sup>CD45RО<sup>+</sup> T CELLS
por: K. A. Yurova, et al.
Publicado: (2018) -
Harnessing CD8<sup>+</sup>CD28<sup>−</sup> Regulatory T Cells as a Tool to Treat Autoimmune Disease
por: Sabrina Ceeraz, et al.
Publicado: (2021)