In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis.

In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis.

PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by human Th1 cells and provides a high degree of protection in vaccinated mice. We evaluated humoral and cellular immune responses induced by a...

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Main Authors: Rym Chamakh-Ayari, Rachel Bras-Gonçalves, Narges Bahi-Jaber, Elodie Petitdidier, Wafa Markikou-Ouni, Karim Aoun, Javier Moreno, Eugenia Carrillo, Poonam Salotra, Himanshu Kaushal, Narender Singh Negi, Jorge Arevalo, Francesca Falconi-Agapito, Angela Privat, Maria Cruz, Julie Pagniez, Gérard-Marie Papierok, Faten Bel Haj Rhouma, Pilar Torres, Jean-Loup Lemesre, Mehdi Chenik, Amel Meddeb-Garnaoui
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/43367cf9df764d0c9cb36074fe25178c
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https://doaj.org/article/43367cf9df764d0c9cb36074fe25178c

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