Controllable Microfluidic Production of Drug-Loaded PLGA Nanoparticles Using Partially Water-Miscible Mixed Solvent Microdroplets as a Precursor

Controllable Microfluidic Production of Drug-Loaded PLGA Nanoparticles Using Partially Water-Miscible Mixed Solvent Microdroplets as a Precursor

Abstract We present a versatile continuous microfluidic flow-focusing method for the production of Doxorubicin (DOX) or Tamoxifen (TAM)-loaded poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs). We use a partially water-miscible solvent mixture (dimethyl sulfoxide DMSO+ dichloromethane DCM...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiang Xu, Shusheng Zhang, Anais Machado, Sébastien Lecommandoux, Olivier Sandre, Frank Gu, Annie Colin
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/433b4b507c3d4ab183de4d7247f01ea8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items