Deletion of an X-inactivation boundary disrupts adjacent gene silencing.
In mammalian females, genes on one X are largely silenced by X-chromosome inactivation (XCI), although some "escape" XCI and are expressed from both Xs. Escapees can closely juxtapose X-inactivated genes and provide a tractable model for assessing boundary function at epigenetically regula...
Enregistré dans:
| Auteurs principaux: | , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/43484e33421944ab9611d15f2d77ef27 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|