De novo design of a reversible phosphorylation-dependent switch for membrane targeting
The ability to dynamically control protein-protein interactions and localization of proteins is critical in synthetic biological systems. Here the authors develop a peptide-based molecular switch that regulates dimer formation and lipid membrane targeting via reversible phosphorylation.
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Autores principales: | Leon Harrington, Jordan M. Fletcher, Tamara Heermann, Derek N. Woolfson, Petra Schwille |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/4376b19d20ae4edab075ab555f27de80 |
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