MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis
ABSTRACT While dispensable for viral replication, coronavirus (CoV) accessory open reading frame (ORF) proteins often play critical roles during infection and pathogenesis. Utilizing a previously generated mutant, we demonstrate that the absence of all four Middle East respiratory syndrome CoV (MERS...
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Auteurs principaux: | Vineet D. Menachery, Hugh D. Mitchell, Adam S. Cockrell, Lisa E. Gralinski, Boyd L. Yount, Rachel L. Graham, Eileen T. McAnarney, Madeline G. Douglas, Trevor Scobey, Anne Beall, Kenneth Dinnon, Jacob F. Kocher, Andrew E. Hale, Kelly G. Stratton, Katrina M. Waters, Ralph S. Baric |
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Format: | article |
Langue: | EN |
Publié: |
American Society for Microbiology
2017
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Sujets: | |
Accès en ligne: | https://doaj.org/article/438eeeef29a24edba2f4d738b85fb4c0 |
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