IgE Trimers Drive SPE-7 Cytokinergic Activity

IgE Trimers Drive SPE-7 Cytokinergic Activity

Abstract Degranulation of mast cells and basophils, with release of agents of the allergic response, ensues when multivalent antigens bind to and cross-link the cells’ receptor-bound IgE antibodies. A widely used commercial monoclonal IgE antibody, SPE-7 IgE from Sigma, was found to possess the radi...

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Autores principales: Heather J. Bax, Holly Bowen, Rebecca L. Beavil, Raymond Chung, Malcolm Ward, Anna M. Davies, Tihomir S. Dodev, James M. McDonnell, Andrew J. Beavil, Brian J. Sutton, Hannah J. Gould
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/43a4bcae3fcb47bd993a61cc883f32f7
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https://doaj.org/article/43a4bcae3fcb47bd993a61cc883f32f7

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