Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance
Mycobacterium tuberculosis exhibits complex evolution of antimicrobial resistance (AMR). Here, the authors perform machine learning and structural analysis to identify signatures of AMR evolution to 13 antibiotics.
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Main Authors: | Erol S. Kavvas, Edward Catoiu, Nathan Mih, James T. Yurkovich, Yara Seif, Nicholas Dillon, David Heckmann, Amitesh Anand, Laurence Yang, Victor Nizet, Jonathan M. Monk, Bernhard O. Palsson |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Subjects: | |
Online Access: | https://doaj.org/article/43c5a44a956f4bc3a0b1035a0afc669c |
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