MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.

Saved in:
Bibliographic Details
Main Authors: Chung-Jung Li, Tian Hong, Ying-Tsen Tung, Ya-Ping Yen, Ho-Chiang Hsu, Ya-Lin Lu, Mien Chang, Qing Nie, Jun-An Chen
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c
Tags: Add Tag
No Tags, Be the first to tag this record!