The inhibitory role of benzo-dioxole-piperamide on the phosphorylation process as an NF-Kappa B silencer

NF-κB contributes to the biosynthesis of various chemokines, cytokines, and enzymes. It plays many crucial roles in the upstream neuroinflammatory pathways. Briefly, the inhibitory IkB subunit is cleaved and phosphorylated by the IKK-α/β enzyme. It leads to the activation and translocation of the NF...

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Bibliographic Details
Main Authors: Sajad Shahbazi, Tara Zakerali
Format: article
Language:EN
Published: Elsevier 2022
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Online Access:https://doaj.org/article/441ce3bc39ca4b4c96c5bfeec3f4c704
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