The inhibitory role of benzo-dioxole-piperamide on the phosphorylation process as an NF-Kappa B silencer
NF-κB contributes to the biosynthesis of various chemokines, cytokines, and enzymes. It plays many crucial roles in the upstream neuroinflammatory pathways. Briefly, the inhibitory IkB subunit is cleaved and phosphorylated by the IKK-α/β enzyme. It leads to the activation and translocation of the NF...
Guardado en:
Autores principales: | Sajad Shahbazi, Tara Zakerali |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://doaj.org/article/441ce3bc39ca4b4c96c5bfeec3f4c704 |
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