Knockout of the <i>hsd11b2</i> Gene Extends the Cortisol Stress Response in Both Zebrafish Larvae and Adults

The Hsd11b2 enzyme converts cortisol into its inactive form, cortisone and regulates cortisol levels, in particular in response to stress. Taking advantage of CRISPR/Cas9 technology, we generated a <i>hsd11b2</i> zebrafish mutant line to evaluate the involvement of this gene in stress re...

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Autores principales: Antonia Theodoridi, Alberto Dinarello, Lorenzo Badenetti, Michail Pavlidis, Luisa Dalla Valle, Aleka Tsalafouta
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/4425acd7a5c44e578290f9888b7f8ef8
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