Knockout of the <i>hsd11b2</i> Gene Extends the Cortisol Stress Response in Both Zebrafish Larvae and Adults
The Hsd11b2 enzyme converts cortisol into its inactive form, cortisone and regulates cortisol levels, in particular in response to stress. Taking advantage of CRISPR/Cas9 technology, we generated a <i>hsd11b2</i> zebrafish mutant line to evaluate the involvement of this gene in stress re...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/4425acd7a5c44e578290f9888b7f8ef8 |
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