Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top...
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Nature Portfolio
2019
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oai:doaj.org-article:44642dfb9cb94830b8332d5e5db86fc02021-12-02T17:01:29ZLongevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait10.1038/s41467-018-07925-02041-1723https://doaj.org/article/44642dfb9cb94830b8332d5e5db86fc02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07925-0https://doaj.org/toc/2041-1723While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort.Niels van den BergMar Rodríguez-GirondoIngrid K. van DijkRick J. MouritsKees MandemakersAngelique A. P. O. JanssensMarian BeekmanKen R. SmithP. Eline SlagboomNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
description |
While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort. |
format |
article |
author |
Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom |
author_facet |
Niels van den Berg Mar Rodríguez-Girondo Ingrid K. van Dijk Rick J. Mourits Kees Mandemakers Angelique A. P. O. Janssens Marian Beekman Ken R. Smith P. Eline Slagboom |
author_sort |
Niels van den Berg |
title |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
title_short |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
title_full |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
title_fullStr |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
title_full_unstemmed |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
title_sort |
longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/44642dfb9cb94830b8332d5e5db86fc0 |
work_keys_str_mv |
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1718382078967414784 |