Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait

While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top...

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Autores principales: Niels van den Berg, Mar Rodríguez-Girondo, Ingrid K. van Dijk, Rick J. Mourits, Kees Mandemakers, Angelique A. P. O. Janssens, Marian Beekman, Ken R. Smith, P. Eline Slagboom
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/44642dfb9cb94830b8332d5e5db86fc0
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spelling oai:doaj.org-article:44642dfb9cb94830b8332d5e5db86fc02021-12-02T17:01:29ZLongevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait10.1038/s41467-018-07925-02041-1723https://doaj.org/article/44642dfb9cb94830b8332d5e5db86fc02019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07925-0https://doaj.org/toc/2041-1723While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort.Niels van den BergMar Rodríguez-GirondoIngrid K. van DijkRick J. MouritsKees MandemakersAngelique A. P. O. JanssensMarian BeekmanKen R. SmithP. Eline SlagboomNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Niels van den Berg
Mar Rodríguez-Girondo
Ingrid K. van Dijk
Rick J. Mourits
Kees Mandemakers
Angelique A. P. O. Janssens
Marian Beekman
Ken R. Smith
P. Eline Slagboom
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
description While human lifespan is only moderately heritable, “getting old” runs in families. Here, van den Berg et al. study mortality data from three-generation cohorts to define a threshold for longevity and find that individuals have an increasing survival advantage with each additional relative in the top 10% survivors of their birth cohort.
format article
author Niels van den Berg
Mar Rodríguez-Girondo
Ingrid K. van Dijk
Rick J. Mourits
Kees Mandemakers
Angelique A. P. O. Janssens
Marian Beekman
Ken R. Smith
P. Eline Slagboom
author_facet Niels van den Berg
Mar Rodríguez-Girondo
Ingrid K. van Dijk
Rick J. Mourits
Kees Mandemakers
Angelique A. P. O. Janssens
Marian Beekman
Ken R. Smith
P. Eline Slagboom
author_sort Niels van den Berg
title Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
title_short Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
title_full Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
title_fullStr Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
title_full_unstemmed Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
title_sort longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/44642dfb9cb94830b8332d5e5db86fc0
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