The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis

Receptor Interacting Protein Kinase 3 (RIPK3) has a key role in TNF-induced necroptosis. Here, the authors combine solid state NMR measurements, MD simulations and cell based assays to characterize mouse RIPK3 and they present the structure of the RIPK3 amyloid core.

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Autores principales: Xia-lian Wu, Hong Hu, Xing-qi Dong, Jing Zhang, Jian Wang, Charles D. Schwieters, Jing Liu, Guo-xiang Wu, Bing Li, Jing-yu Lin, Hua-yi Wang, Jun-xia Lu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/446eaf68a95446b2b5bed797c3cf78f3
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