Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Zinc is a potent and specific inhibitor of IFN-λ3 signalling

Lambda interferons (IFNL) are involved in the immune response to viral infection. Here the authors show that zinc can interfere with IFNL signalling, and that in HCV patients the rs12979860 polymorphism regulates blood zinc levels and, subsequently, the hepatic immune response.

Saved in:
Bibliographic Details
Main Authors: Scott A. Read, Kate S. O’Connor, Vijay Suppiah, Chantelle L. E. Ahlenstiel, Stephanie Obeid, Kristina M. Cook, Anthony Cunningham, Mark W. Douglas, Philip J. Hogg, David Booth, Jacob George, Golo Ahlenstiel
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/448cc0a156b540329808e92d9913726d
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/448cc0a156b540329808e92d9913726d

Similar Items