HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?

Exosomes are secreted cellular vesicles that can induce specific CD4(+) T cell responses in vivo when they interact with competent antigen-presenting cells like mature dendritic cells (mDCs). The Trojan exosome hypothesis proposes that retroviruses can take advantage of the cell-encoded intercellula...

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Auteurs principaux: Nuria Izquierdo-Useros, Mar Naranjo-Gómez, Itziar Erkizia, Maria Carmen Puertas, Francesc E Borràs, Julià Blanco, Javier Martinez-Picado
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/44b7853429764e1390f264bef1ff14e5
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